2-(2-METHOXY PHENOXY) ETHYL AMINE (BASE)

Product Description

22Methoxyphenoxyethylamine Base is the freebase form of the compound differing from the hydrochloride salt by the absence of the protonated amine and chloride counterion Below is a detailed description

 Chemical Information

•  Chemical Name 22Methoxyphenoxyethylamine Base  
•  Chemical Formula C9H13NO2  
•  Molecular Weight 16721 gmol  

 Structure  

•    Phenoxy Group A benzene ring substituted with a methoxy group OCH3 at the 2nd position and linked via an ether bond O to the ethyl chain  
•    Amino Group NH2 Attached to the terminal carbon of the ethyl chain

 Physical Properties

•  Appearance A clear liquid or paleyellow solid depending on temperature and purity  
•  Melting Point Usually lower than the hydrochloride salt due to the absence of ionic interactions  
•  Boiling Point Approximately 260280C  

 Solubility  

•    Soluble in organic solvents like ethanol methanol or acetone  
•    Slightly soluble in water compared to its hydrochloride salt

 Applications

Pharmaceutical Intermediate  

•     Used in the synthesis of therapeutic agents such as betablockers and adrenergic receptor modulators  
•     Key precursor in the production of antihypertensive and antiarrhythmic drugs

Organic Synthesis  

•     Versatile intermediate for creating more complex molecules in research and chemical industries  
•     Phenoxy and amine groups make it amenable to further functionalization

Material Science  

• Used as a building block for creating polymers or advanced materials with specific properties

 Safety and Handling

 Hazards  

•    Flammable keep away from heat and open flames  
•    May cause irritation to the skin eyes and respiratory tract Avoid prolonged exposure  

 Handling  

•    Use standard laboratory precautions gloves goggles and lab coat  
•    Ensure work is conducted in a fume hood or wellventilated area  

 Storage  

•    Store in a tightly sealed container in a cool dry and ventilated area  
•    Protect from exposure to light and moisture

 Reactivity

 Functional Groups  

•    Amino Group NH2 Highly reactive can participate in acylation alkylation or Schiff base formation  
•    Ether Bond O Chemically stable under neutral conditions but may degrade under strong acidic or basic environments  
•    Methoxy Group OCH3 Electrondonating enhances reactivity of the benzene ring in electrophilic substitution reactions

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